A close-up of a lion's mane mushroom in a bowl

Lion's Mane

In this post, we'll explore the many health benefits of lion's mane mushroom and how you can incorporate it into your daily routine.

What is Lion's Mane Mushroom?

Lion's mane mushroom is a white, shaggy mushroom commonly used for cooking and medicine in China, India, Japan, and Korea. It contains bioactive compounds that benefit the digestive tract, heart, and brain. The fruit body of the lion's mane mushroom has been found to accelerate brain cell growth which may help protect against Alzheimer's disease as well as reduce mild depression and anxiety. While research on humans is still needed to fully understand its benefits for human health, it has shown promising results in animal studies.

Description of the Mushroom Fruiting Body

The anatomy and physical characteristics of the lion's mane mushroom fruiting body are unique. These large, white mushrooms have a shaggy appearance and consist of distinct parts such as the cap and stem. The compounds found in the fruit body provide numerous health benefits due to their nutritional composition. Research has shown that lion's mane mushroom extracts contain hericenones, erinacines, beta-glucans, and antioxidants that offer therapeutic properties.

Nutritional composition:

  • Beta-glucans
  • Antioxidants
  • Proteins
  • Carbohydrates

Health benefits:

  • Promotes brain cell growth
  • Protects against Alzheimer's disease
  • Reduces mild depression and anxiety
  • May speed nervous system recuperation

Research-backed therapeutic properties:

  • Hericenones
  • Erinacines

History and Traditional Uses in Different Cultures

The Lion's Mane mushroom has been used in traditional Chinese medicine for centuries to treat digestive problems, reduce inflammation, and enhance cognitive function. In addition to China, other cultures such as Japan and Korea also use this mushroom both medicinally and in their cuisine. More recently, the fruit body of the Lion's Mane mushroom has gained popularity in Western wellness culture due to its potential health benefits, including improving brain function and reducing symptoms of anxiety and depression. Its compounds have also been studied for their potential to speed up nerve cell growth and repair damage caused by strokes or spinal cord injuries.

Health Benefits of Lion's Mane Mushroom

A vibrant, sun-drenched lion's mane mushroom nestled in a lush

Lion's mane mushrooms have been shown to promote brain cell growth and protect against Alzheimer's disease, making them beneficial for preventing dementia. Additionally, these mushrooms may reduce symptoms of mild depression and anxiety by promoting hippocampal health in animal experiments. Lion's mane extract has also been found to speed the recovery of nerve cells and prevent stomach infections by inhibiting H bacteria growth. Furthermore, studies show that lion's mane extract can lower triglycerides and decrease weight gain, ultimately reducing the risk of cardiovascular disease.

Prevents Dementia

Lion's mane mushroom is a potent supplement that prevents dementia by boosting cognitive function and slowing down cognitive decline in elderly individuals. It also protects against Alzheimer's disease by preventing memory loss and protecting neurons from amyloid-beta plaques. While most research on its benefits has been conducted on animals or in test tubes, a 2020 study found that supplementing with one gram of the mushroom daily for 49 weeks significantly improved cognitive test scores in moderate Alzheimer's patients.

Reduces Mild Depression and Anxiety

Lion's mane mushroom extract has been found to have potential benefits in reducing mild depression and anxiety. Animal studies show that the extract can promote hippocampal health, reduce anxious and depressive behaviors, and improve brain cell regeneration. A small study of menopausal women also found that eating lion's mane mushroom biscuits daily for a month reduced irritation and anxiety. While more human studies are needed, these findings suggest that lion's mane mushrooms could be a helpful supplement for those dealing with symptoms of anxiety or depression.

  • Supports mental clarity and focus
  • May alleviate symptoms of anxiety disorders
  • May improve mood and decrease feelings of depression

May Speed Nervous System Recuperation

Lion's mane mushrooms are a helpful supplement for nerve-related injuries or conditions. Research suggests that lion's mane extract stimulates nerve growth and increases repair, potentially improving recovery time. Additionally, lion's mane extract decreases inflammation that contributes to the healing process by reducing stroke-related brain damage. While more human research is needed, these findings suggest that incorporating lion's mane into one's diet may be beneficial for nervous system recuperation.

Prevents Stomach Infections

Lion's mane mushroom extract can prevent stomach infections and gastric ulcers from developing. It improves gut health by inhibiting bacterial growth, including the harmful Helicobacter pylori bacteria that causes many stomach problems. The antibacterial properties of lion's mane mushrooms make it a natural way to fight off bacterial infections in the digestive system.

Preventing Cardiovascular Disease

Lion's mane mushrooms' benefits go beyond brain health and can decrease the risk of cardiovascular disease. Here are some ways they can help:

  • Lowers blood pressure levels: Lion's mane extract increases fat metabolism and decreases triglycerides, which in turn lower overall blood pressure.
  • Inhibits plaque accumulation in arteries: The extract reduces circulatory cholesterol oxidation in test tubes, preventing arterial wall stiffening that leads to heart attacks and strokes.
  • Decreases cholesterol levels: Mice fed a high-fat diet with lion's mane extract daily for 28 days had significantly lower triglycerides.

Overall, adding lion's mane supplements to your routine may improve your cardiovascular health by reducing obesity, lowering blood pressure levels, and protecting against arterial damage caused by oxidized cholesterol molecules.

Side Effects of Lion's Mane Mushroom

It is important to note the potential side effects of consuming lion's mane mushroom. One possible side effect is blood-thinning, which can be harmful for those taking anticoagulant medications or with bleeding disorders. Additionally, some individuals may experience allergic reactions such as rashes or swelling after consuming lion's mane mushroom. It is also advised that individuals with diabetes consult their doctor before using this supplement as it may interact with certain medications. As always, it is best to speak with a healthcare professional before adding any new supplements to your routine.

Allergic Reactions

Allergic reactions to Lion's Mane mushroom can cause symptoms such as hives, itching, and swelling. Those with a history of allergies should exercise caution when using this supplement. Risk factors for developing an allergy include genetic predisposition and exposure to other allergens. Precautions that individuals with allergies should take when using Lion's Mane mushroom include starting with a small dose, monitoring symptoms closely, and consulting a healthcare provider before use. It is important to note that allergic reactions can be severe or life-threatening in some cases, so it is essential to seek medical attention immediately if any serious symptoms occur.

Blood-Thinning Effects

Lion's mane mushroom may have blood-thinning effects due to its ability to inhibit platelet aggregation and reduce clotting. This could be beneficial for those at risk of heart disease or stroke, but caution should be taken if using lion's mane alongside anticoagulant drugs as there is a potential for interactions. If you are on blood-thinning medication, it is advisable to consult with your doctor before taking lion's mane mushroom supplements or making any changes to your medication regimen.

Interaction with Diabetes Medications

As a diabetic, it's important to be aware of the potential effects of Lion's Mane mushroom on your blood sugar levels. While studies have shown that Lion's Mane extract may reduce blood glucose levels in animals, more research is needed to confirm these effects in humans. Additionally, there may be possible interactions between diabetes medications and Lion's Mane supplement use, so caution should be taken when using them together.

Precautions to take when using Lion's mane supplements as a diabetic:

  • Monitor blood sugar levels closely
  • Consult with your healthcare provider before taking any new supplements or making changes to your medication regimen
  • Start with low doses and gradually increase as tolerated
  • Be aware of potential side effects such as nausea or stomach discomfort

How to Take Lion's Mane Mushroom

Serenity Mushroom Extract

To take lion's mane mushroom supplements, it is recommended to follow the manufacturer's dosing instructions. Lion's mane can be taken in various forms such as capsules, powders or teas. It is best to start with a low dose and gradually increase as needed over time.

For optimal results, it is suggested that lion’s mane extract should be consumed for an extended period of time ranging from several weeks to months. However, if you experience any negative side effects like gastrointestinal discomfort or allergic reactions stop consuming it immediately and consult your healthcare provider.

Remember that while there are plenty of health benefits associated with taking lion's mane supplements, more human research needs to be conducted to fully understand its potential efficacy on humans.

Forms of Lion's Mane Mushroom Supplements

Lion's Mane mushroom supplements come in different forms, including powder form, capsule form, and tincture or liquid extract. The powder form is easy to mix into drinks or smoothies for a quick supplement boost. Capsules offer precise dosing and are convenient for on-the-go use. Tinctures and liquid extracts have a faster absorption rate than other forms but may not be as readily available as powders or capsules.

It's important to note that the effectiveness of Lion's Mane supplements depends on the quality of the mushroom fruiting body used in their production. Look for supplements made from high-quality fruiting bodies to ensure maximum benefits.

Dosing and Duration of Use

For beginners, a daily dose of 100 - 750 mg of lion's mane mushroom extract is recommended. Gradually increasing the dosage over time can help maximize benefits and minimize potential side effects. It is important to note that there are no established guidelines for how long to use lion's mane mushrooms, but most studies have used supplements for at least four weeks to see positive results. As always, it is best to consult with a healthcare provider or nutritionist before starting any new supplement regimen.

Possible Drug Interactions

Cautionary note on blood-thinning medications: Lion's mane mushroom supplements may interact with blood thinning medications such as warfarin. Consult a doctor before taking lion's mane supplements if you are taking these types of medications.

Talk to your doctor for advice for those taking other supplements or medications: If you are currently taking any other herbal supplements or prescription medication, it is important to talk to your doctor before adding lion's mane mushroom fruiting body extract to your regimen. This will help prevent potential interactions and ensure optimal health benefits from both the supplement and any other treatments you may be receiving.

Why it is important to seek medical advice before taking Lion’s Mane mushroom supplements: While there is promising preliminary research on the health benefits of lion’s mane mushrooms, it is crucial to seek medical advice from a healthcare provider before starting supplementation. This will help identify any potential risks related to existing health conditions or medication use, and determine an appropriate dosage based on individual needs.


Mushroom fruiting bodies, such as Lion's Mane, have been shown to offer a range of health benefits. These include promoting muscle growth and improving cognitive function. Incorporating Lion's Mane into your supplement routine can provide a natural and effective way to support your fitness goals.

In addition to its physical benefits, Lion's Mane has also been found to enhance mood and reduce symptoms of anxiety and depression. Its neuroprotective properties make it an excellent choice for those looking for a supplement that supports both their physical and mental well-being.

Kayla Thomas


Kayla Thomas, a 34-year-old sports and fitness coach living in Connecticut, USA. With seven years of hands-on experience, she's all about helping folks get fit and strong. Kayla's fitness journey began when she was a sports-loving kid, and she followed her passion to college, where she earned a degree in Exercise Science and picked up personal training and sports coaching certifications. But what really lights her up is empowering women through fitness, breaking barriers and making fitness feel welcoming for everyone. Her clients see her as not just a coach but a motivating friend. In her downtime, you'll find her swimming and cycling, always on the move. And you can follow her fitness journey on Instagram – she's all about sharing that empowerment vibe.